Example of MRI/TRUS-fusion guided biopsy using the MedCom system. MRI-targeted biopsy with ultrasound guidance and software registration. Series showing (from left to right): T2-weighted image showing a low-intensity lesion in the left peripheral zone, delineation of the target volume on the T2-weighted image, a three-dimensional model of prostate volume and target volume, registration of MR volume to ultrasound image, and the biopsy needle within the target volume on the ultrasound image. MRI, magnetic resonance imaging; TRUS, transrectal ultrasound.