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Graph bar showing mean values of number of mast cell infiltration per square millimetre of urinary bladder mucosa. Animals subcutaneously receiving 2.5 mg of PHE per kg of body weight (PHE 2.5 mg/kg, n=4), for 14 days, presented more mast cells than control animals (**, P<0.01, n=4). Pre-treatment with 75 mg CAP before the PHE treatment (PHE 2.5 mg/kg + CAP, n=4) reverse the PHE induced mast cell infiltration. PHE, phenylephrine; CAP, capsaicin; *, P<0.05.
