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. Author manuscript; available in PMC: 2016 Jan 11.
Published in final edited form as: Free Radic Biol Med. 2012 Apr 19;53(3):618–628. doi: 10.1016/j.freeradbiomed.2012.03.025

Fig. 6.

Fig. 6

Upregulation of TCA cycle proteins in LS12 cells. Analysis of the mitochondrial subproteome demonstrates that, in addition to proteins involved in β oxidation, seven of nine TCA proteins are upregulated in LS12 cells, suggesting increased TCA cycle activity in compensation for ETC defects. Gray, proteins not identified in proteomic and MS analysis; pink, proteins identified in proteomic and MS analysis as upregulated (*p<0.05); red, proteins validated in subsequent enzyme activity assays.