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. Author manuscript; available in PMC: 2016 Feb 1.
Published in final edited form as: Free Radic Biol Med. 2014 Oct 5;79:237–250. doi: 10.1016/j.freeradbiomed.2014.09.027

Table 1.

Intrinsic and GEF-mediated GDP dissociation rates for Rac1WT, Rac1C18S, Rac1C18A, Rac1C18D, and Rac1S–SG.

Rac1 construct koff (s−1) intrinsic Fold increase (relative to WT) koff (s−1) with Tiam1
Rac1WT 0.71 ± 0.02 × 10−4 – 5.02 ± 0.01 × 10−4
Rac1C18S 0.81 ± 0.00 × 10−4 1.1 4.28 ± 0.03 × 10−4
Rac1C18A 7.58 ± 0.02 × 10−4 10.7 n/d
Rac1C18D 157.87 ± 1.38 × 10−4 222.4 114.73 ± 0.61 × 10−4
Rac1S–SG 167.50 ± 25.13 × 10−4 235.9 n/d