Table 2.
Intrinsic and GAP-mediated GTP hydrolysis rates for Rac1WT, Rac1C18S, and Rac1C18D.
Rac1 construct | Intrinsic GTP hydrolysis (s−1) | p50 rhoGAP GTP hydrolysis (s−1) |
---|---|---|
Rac1WT | 0.90 ± 0.07 × 10−3 | 4.8 ± 0.1 × 10−3 |
Rac1C18S | 1.50 ± 0.11 × 10−3 | 5.5 ± 0.3 × 10−3 |
Rac1C18D | 0.26 ± 0.01 × 10−3 | 4.9 ± 0.2 × 10−3 |