Figure 2.

Increasing doses of photodynamic therapy (PDT) drug or gamma irradiation results in a reduction and ablation of colony‐forming ability in primary prostate epithelial cells and an increase in production of Reactive Oxygen Species (ROS). Primary prostate epithelial cells from four patients were treated with varying doses of PDT drug (A) or gamma irradiation (B), and the colony‐forming ability was assessed after 7 days of growth. Colony‐forming ability is presented as % surviving fraction. Primary prostate epithelial cells were treated with increasing doses of (C) PDT drug or (D) gamma irradiation and the production of ROS was measured using the ROS‐Glo assay (Promega).