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. 2015 Dec 8;5(1):24–32. doi: 10.1002/cam4.564

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© 2015 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Kaplan–Meier estimates effect of genotype in rs33933140 and dosimetric parameters on RP‐free survival (RP ≥ grade 3). (A) rs33933140 and MLD; (B) rs33933140 and V₂₀. Patients with AA genotype of AKT2: rs33933140 and MLD ≥ 15 Gy or V₂₀ ≥ 24% had the highest risk of RP grade ≥ 3 compared with other groups (P < 0.0001 and P < 0.0001, respectively).