Table 3.
Reference number | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|
OS (%) | 3y (86.3) | 2y (78) | 2y (80.1) | 2y (86) | 2y (88.5) |
PFS (%) | 3y (85.2) | 2y (67) | 2y (81) | 2y (86) | 2y (80.6) |
Age (%) | |||||
Less than or equal to 60 years | 86.7 | 74 | 94.7 | 85.2 | 84.6 |
Older than 60 years | 13.3 | 26 | 5.3 | 14.8 | 15.4 |
Sex (%) | |||||
Male | 56.7 | 63 | 63.2 | 59.3 | 73 |
Female | 43.3 | 37 | 36.8 | 40.7 | 27 |
ECOG performance status (%) | |||||
0 | 56.7 | 78 | 34.2a | 18.5 | 57.7 |
1 | 43.3 | 15 | 63.2 | 66.7 | 38.5 |
2 | / | 7 | 2.6 | 14.8 | 3.8 |
Ann Arbor stage (%) | |||||
I | 50 | 67 | 52.6a | 66.7 | 76.9 |
II | 50 | 33 | 28.9 | 33.3 | 23.1 |
III/IV | / | / | 18.4 | / | / |
LDH (%) | |||||
Normal | 80 | 81 | 81.4a | 88.9 | 61.5 |
Increased | 20 | 19 | 18.6 | 11.1 | 38.5 |
B symptoms (%) | |||||
Present | 36.7 | 37 | 57.9a | 37 | 34.6 |
Absent | 63.3 | 63 | 42.1 | 63 | 65.4 |
EBV titration (%) | |||||
At least 64 copies/μL | 36.7a | / | / | / | / |
Lower than 64 copies/μL | 63.3 | / | / | / | / |
Regional node (%) | |||||
Yes | 36.7 | / | 47.4 | 40.7 | / |
No | 63.3 | / | 52.6 | 59.3 | / |
IPI scores (%) | |||||
0 | 76.7 (0–1) | 59 | 71.1 (0–1)a | 81.5 | 50 |
1 | 30 | 18.5 | 42.3 | ||
2 | 23.3 | 11 | 18.4 | / | 7.7 |
3 | / | / | 5.3 | / | / |
4‐5 | / | / | 5.3 | / | / |
NKIPI scores (%) | |||||
0 | / | 26.3a | / | ||
1 | 70 (1–2) | 33 | 34.2 | / | 69 (1–2) |
2 | 30 | 18.4 | / | ||
3 | 30 (3–4) | 26 | 21.1 (3–4) | / | 31 (3–4) |
4 | 11 | / | |||
Platelet count (%) | |||||
Lower than or equal to 150 000/mm3 | 10a | / | / | / | / |
Higher than 150 000/mm3 | 90 | / | / | / | / |
Lymphocyte count (%) | |||||
Lower than or equal to 1000/mm3 | 23.3a | / | / | / | / |
Higher than 1000/mm3 | 76.7 | / | / | / | / |
CRa (%) | 80 | 77 | 81.6 | 74.1 | 80.8 |
ORR (%) | 83.3 | 81 | 84.2 | 96.3 | 88.5 |
OS, Overall survival; PFS, Progression‐free survival; CR, complete response; ORR, overall response rates; ECOG, Eastern Cooperative Oncology Group; EBV, Epstein–Barr virus; LDH, lactate dehydrogenase; IPI: International Prognostic Index; NKIPI, Korea natural killer/T‐cell lymphoma Prognostic Index.
Prognostic factors.