Table 3.
Univariate analyses of the associations between pCR and body fat distribution parameters
| Variables | No. of non‐pCR patients (n = 126) | % | No. of pCR patients (n = 46) | % | P |
|---|---|---|---|---|---|
| Age (year, median, range) | 55 (30–76) | 53 (32–75) | 0.63 | ||
| BMI (kg/m2, average, ±SD) | 22.8 ± 3.9 | 23.0 ± 3.7 | 0.74 | ||
| WHO BMI classification | |||||
| Underweight (BMI < 18.5 kg/m2) | 14 | (11) | 4 | (9) | 0.88 |
| Normal range (18.5 ≤ BMI < 25 kg/m2) | 81 | (64) | 30 | (65) | |
| Overweight (25 ≤ BMI < 30 kg/m2) | 26 | (21) | 9 | (20) | |
| Obese (BMI ≥ 30 kg/m2) | 5 | (4) | 3 | (7) | |
| Subcutaneous fat area (cm2, average ± SD) | 134 ± 66 | 148 ± 64 | 0.22 | ||
| Visceral fat area (cm2, median, range) | 73 (5–317) | 81 (10–217) | 0.53 | ||
| V/S ratio (%, median, range) | 54.0 (15–223) | 47.5 (19–127) | 0.32 | ||
| Lumber skeletal muscle index (cm2/cm3, average ± SD) | 57.5 ± 7.6 | 57.6 ± 7.2 | 0.94 | ||
| Liver/Spleen HU ratio (median, range) | 1.3 (1–2) | 1.2 (0.1–2) | 0.38 | ||
| Menopausal status | |||||
| Pre | 53 | (42) | 21 | (46) | 0.67 |
| Post | 73 | (58) | 25 | (54) | |
| T | |||||
| 2 | 84 | (67) | 36 | (78) | 0.33 |
| 3 | 19 | (15) | 5 | (11) | |
| 4 | 23 | (18) | 5 | (11) | |
| Histological type | |||||
| Ductal | 112 | (89) | 28 | (61) | <0.05 |
| Other | 14 | (11) | 18 | (39) | |
| Subtype | |||||
| ER (+), HER2 (−) | 68 | (54) | 9 | (20) | <0.05 |
| ER (+), HER2 (+) | 21 | (17) | 9 | (20) | |
| HER2 | 17 | (13) | 17 | (37) | |
| Triple‐negative | 20 | (16) | 11 | (24) | |
pCR, pathological complete response; WHO, world health organization; BMI, body mass index; SD, standard deviation; V/S ratio, visceral fat area/subcutaneous fat area ratio; HU, hounsfield unit: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2.