Figure 2. LCN2 protein levels in CSF and LCN2 index in patients with MS and controls.

CSF levels of lipocalin-2 (LCN2) and LCN2 index values in (A, B) symptomatic controls (SC), inflammatory neurologic disease controls (INDC), and patients with multiple sclerosis (MS); in (C, D) patients with relapsing-remitting MS (RRMS), secondary progressive MS (SPMS), and primary progressive MS (PPMS); and in (E, F) patients in RRMS remission and RRMS relapse. *p < 0.05 and ***p < 0.001.