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. 2016 Jan 7;3(1):e191. doi: 10.1212/NXI.0000000000000191

Figure 4. Early but not late exposure of myelinating cultures to LCN2 inhibits myelination.

Figure 4

(A) Representative images taken from untreated myelinating cultures (A.a) or after treatment with 1,000, 100, or 10 ng/mL of lipocalin-2 (LCN2) (A.b–A.d, respectively) with quantification of immunochemical data (B). Untreated myelinating cultures at 24 days in vitro (DIV) (C.a), 30 DIV (C.b), or after addition of 1 µg/mL LCN2 at 24–30 DIV (C.c) with quantification of immunochemical data (C.d.). phosphorylated neurofilament: red; myelin oligodendrocyte glycoprotein: green; scale bar = 100 µm. *p < 0.05, **p < 0.01.