Table 1.
Baseline demographics and clinical characteristics of patients with acne vulgaris and healthy controls.
| Characteristic | Patients with acne vulgaris (n=39) | Healthy controls (n=40) | P-value |
|---|---|---|---|
| Gender | 0.86 | ||
| Female | 28 (71.8%) | 28 (70.0%) | |
| Male | 11 (28.2%) | 12 (30.0%) | |
| Age, years | 0.04 | ||
| MeanSD | 24.23±6.45 | 27.18±5.87 | |
| Median (range) | 23 (12–42) | 28 (16–42) | |
| BMI | 0.27 | ||
| MeanSD | 22.58±3.57 | 23.56±4.07 | |
| Sun-exposure time > 2 hours per day | 11 (28.2%) | 4 (10.0%) | 0.04 |
| Positive family history of acne | 26 (66.7%) | 26 (65.0%) | 0.88 |
| Hirsutism# | 13 (46.4%) | 8 (28.6%) | 0.17 |
| PCOS# | 12 (42.9%) | 3 (10.7%) | 0.01 |
| Age at onset of disease, years | |||
| Median (range); IQR | 17 (10–29); (15–19) | - | |
| Duration of disease, years | |||
| Median (range); IQR | 5 (1–25); (2–10) | - | |
| Site of acne | - | ||
| Face | 19 (48.7%) | ||
| Trunk | - | ||
| Both | 20 (51.3%) | ||
| Active acne | 39 (100%) | - | |
| GAGS | - | ||
| MeanSD | 24.92±10.57 | - | |
| GAGS categories* | - | ||
| Mild | 12 (30.8%) | ||
| Moderate | 17 (43.6%) | ||
| Severe | 5 (12.8%) | ||
| Very severe | 5 (12.8%) | ||
Values are no. (%) unless otherwise noted.
Abbreviations: BMI, Body Mass Index (calculated as weight in kilograms divided by height in meters squared); IQR, Interquartile range (25th –75th percentiles); PCOS, Polycystic ovary syndrome; GAGS: Global Acne Grading System.
#
the proportions were calculated in the group of females;
*
A GAGS score of 1–18 is considered mild; 19–30, moderate; 31–38, severe; and >39, very severe.