Table 2.
Serum concentrations of 25-hydroxyvitamin D [25 (OH) D].
| 25 (OH) D | Patients with acne vulgaris (n=39) | Healthy controls (n=40) | P-value |
|---|---|---|---|
| 25 (OH) D, ng/mL | 8.4 (1.4–99); (5–14.1) | 10.4 (3.1–56.7); (6.58–20.25) | 0.14 |
| 25 (OH) D categories#, no. (%) | |||
| Severe vitamin D deficiency | 24 (61.5%) | 20 (50.0%) | |
| Moderate vitamin D deficiency | 9 (23.1%) | 10 (25%) | |
| Vitamin D insufficiency | 2 (5.1%) | 6 (15%) | |
| Vitamin D sufficiency | 4 (10.3%) | 4 (10%) | |
| Sun-exposure time | |||
| < 2 hours per day | 8.25 (1.4–99); (4.05–14.62) | 10.4 (3.1–56.7); (6.58–20.08) | |
| ≥ 2 hours per day | 8.5 (3.3–22.2); (7.7–14.1) | 13.5 (5.5–21); (6–20.62) | |
| GAGS* | - | ||
| Mild (n=12) | 8.45 (1.7–34.6); (3.08–16.35) | ||
| Moderate (n=17) | 8.6 (1.4–99); (7.2–21.3) | ||
| Severe/very severe(n=10) | 7.05 (3.3–12.8); (3.7–10.3) | ||
Values are median (range); IQR of serum 25-hydroxyvitamin D, unless otherwise stated.
Abbreviations: IQR, Interquartile range (25th–75th percentiles); GAGS: Global Acne Grading System
#
Subjects were divided into four categories: Severe vitamin D deficiency [25(OH)D <10 ng/ml], moderate vitamin D deficiency [25(OH)D 10 to <20 ng/ml], vitamin D insufficiency [25(OH)D 20 to <30 ng/ml] and vitamin D sufficiency [25(OH)D≥30 ng/ml]
*
A GAGS score of 1–18 is considered mild; 19–30, moderate; 31–38, severe; and >39, very severe