Table 3B.

Changes in Electrophysiologic and JND Variables Between Baseline and Six Months, by Leg and Treatment Group

Treatment Group	VEGF	Placebo	P value
Changes in Electrophysiologic Variables (Median, Interquartile Range)
Tibial Amplitude
Untreated Leg	0.0 (−0.3, 0.1)	−0.1 (−1.3, 0.0)	0.33
Treated Leg	0.0 (−0.2, 0.1)	−0.4 (−2.3, 0.0)	0.27
Peroneal Amplitude
Untreated Leg	0.0 (−0.2, 0.1)	0.0 (−0.3, 0.6)	0.88
Treated Leg	0.0 (−0.3, 0.0)	0.0 (−0.1, 0.9)	0.12
Amplitude Sum
Untreated Leg	0.0 (−0.3, 0.1)	0.0 (−3.0, 0.4)	0.80
Treated Leg	−0.1 (−0.4, 0.0)	0.0 (−1.0, 0.1)	0.64
Sural Amplitude
Untreated Leg	0.0 (0.0, 0.0)	0.0 (−0.5, 0.0)	0.44
Treated Leg	0.0 (0.0, 0.0)	0.0 (−0.8, 0.0)	0.36
Changes in JND Measurements (Mean, Standard Error)
Cold
Untreated Leg	−0.15 (1.11)	−3.14 (3.98)	0.31
Treated Leg	−0.68 (1.21)	2.01 (4.65)	0.30
Vibration
Untreated Leg	0.84 (0.81)	−1.66 (1.31)	0.15
Treated Leg	0.07 (0.88)	−0.43 (0.51)	0.69