Figure 1. Nur77 in immune and vascular cells.

Nur77 function has been studied in T-cells, monocytes, macrophages, endothelial cells and smooth muscle cells and the outcome of these analyses is indicated in boxes at the specific cell types. For Nurr1 and NOR1 less information is available, but overall Nurr1 appears to have similar functions in these cell types as Nur77, whereas NOR-1 mostly mediates opposite effects.