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Complete response rate. No correlation between cumulative dose of gemcitabine and complete response (CR) rate was observed. Importantly, very low-dose regimens integrating cumulative doses of gemcitabine <300 mg/m2 (roughly corresponding to 50 mg/m2 per week) still managed to yield a CR rate of 86% (95% CI, 74%–93%) [39, 52, 53]. Studies numbered 4 [41] and 13 [48] were not included in the analysis because only global response rates were given instead of a dose-specific response rate.
