Number of annual/yearly (1975–2013) results (“hits”) in a PubMed search using the word “newborn” in combination with “pharmacotherapy,” “pharmacokinetics,” and “drug.” Compared to the 1975–1980 observations, there is a 2–4-fold increase in hits (black line “newborn and drug,” dark gray line “newborn and pharmacotherapy,” light gray line “newborn and pharmacokinetics”).