Figure 7. Orthologous endogenous viral elements (EVEs) derived from filovirus nucleoprotein (NP) genes indicate that filoviruses have infected bats for at least 25 million years.
The time-calibrated phylogeny shown to the left is based on estimates obtained in Miller-Butterworth et al., 2007. The schematic to the right shows the orthologous EVEs and empty insertion sites as they occur in each bat genome. Also see Supplementary file 5.