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. 2016 Jan 11;5:1. doi: 10.1186/s40169-015-0080-3

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© Bussey et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — High PLK1 mRNA expression is associated with worse prognosis in ACC tumors. a In data from Affymetrix U133 plus 2 arrays, tumors that exhibit a log2 fold-change of 2 or greater relative to normal have a worse overall survival compared to tumors that express less PLK1 mRNA. b The relationship between PLK1 mRNA expression and shorter survival times was validated by RNA sequencing data from TCGA. c In the TCGA data set, the only clinical parameter associated with PLK1 expression is residual tumor status