. 2014 Jul 17;3:61–102. doi: 10.1007/s40204-014-0026-7

Table 2.

Composition of natural bone matrix

Composition	Content and function
Biological ceramic	Carbonated HA Ca₁₀(PO₄)₆(OH)₂ accounts for approximately 70 % of the weight of bone. The inorganic component provides compressive stiffness to bone
Biological polymer	Roughly one-third of the weight of bone is composed of the organic matter, which is primarily type I collagen and ground substance. Type I collagen fibres are elastic and flexible, and thus tolerate stretching, twisting, and bending. Bone collagen differs slightly from soft-tissue collagen of the same type in having a great number of intermolecular cross-links. Ground substance contains proteoglycans aggregates and several specific structural glycoproteins

Composition

Content and function

Biological ceramic

Carbonated HA Ca₁₀(PO₄)₆(OH)₂ accounts for approximately 70 % of the weight of bone. The inorganic component provides compressive stiffness to bone

Biological polymer

Roughly one-third of the weight of bone is composed of the organic matter, which is primarily type I collagen and ground substance. Type I collagen fibres are elastic and flexible, and thus tolerate stretching, twisting, and bending. Bone collagen differs slightly from soft-tissue collagen of the same type in having a great number of intermolecular cross-links. Ground substance contains proteoglycans aggregates and several specific structural glycoproteins