Table 4.
Important bioactive compounds isolated from Swertia chirayita.
| Phytochemical | Biological activity | References |
|---|---|---|
| Amarogentin | Antileishmanial | Ray et al., 1996; Medda et al., 1999 |
| Topoisomerase inhibitor | Ray et al., 1996 | |
| Anticancer | Saha et al., 2006; Pal et al., 2012 | |
| Anti-diabetic | Phoboo et al., 2013 | |
| Gastroprotective | Niiho et al., 2006 | |
| Swertiamarin | CNS depressant | Bhattacharya et al., 1976 |
| Anticholinergic | Suparna et al., 1998 | |
| Anticancer | Kavimani and Manisenthlkumar, 2000 | |
| Anti-hepatitis | Wang et al., 2001 | |
| Antibacterial | Kumarasamy et al., 2003 | |
| Cardio-protective, anti-atherosclerotic | Vaidya et al., 2009 | |
| anti-diabetic | Vaidya et al., 2013 | |
| Anti-arthritic | Saravanan et al., 2014 | |
| Mangiferin | Antiviral | Zheng and Lu, 1990 |
| Immunomodulatory, antitumor, anti-HIV | Guha et al., 1996 | |
| Antioxidant | Sanchez et al., 2000 | |
| Chemopreventive | Yoshimi et al., 2001 | |
| Antiinflammatory | Kumar et al., 2003 | |
| Hypoglycemic | Muruganandan et al., 2005 | |
| Anti-diabetic, Antiatherosclerotic | Pardo-Andreu et al., 2008 | |
| Antiparkinson | Kavitha et al., 2013 | |
| Swerchirin | Hypoglycemic | Bajpai et al., 1991; Saxena et al., 1996 |
| Hepatoprotective, pro-heamatopoietic | Ya et al., 1999 | |
| Blood glucose lowering activity | Sekar et al., 1987; Saxena et al., 1993 | |
| Chemopreventive | Hirakawa et al., 2005 | |
| Sweroside | Antibacterial | Siler et al., 2010 |
| Hepatoprotective | Liu et al., 1994; Luo et al., 2009 | |
| Hyperpigmentation | Jeong et al., 2015 | |
| Osteoporosis | Sun et al., 2013 | |
| Amaroswerin | Gastroprotective | Niiho et al., 2006 |
| Gentianine | Antipsychotic | Bhattacharya et al., 1974 |
| Antimalarial | Natarajan et al., 1974 | |
| Oleanolic acid | Antimicrobial | Jesus et al., 2015 |
| Antitumor | Soica et al., 2014 | |
| Antiinflamatory, antioxidant | Liu, 1995 | |
| Ursolic acid | Antimicrobial | Jesus et al., 2015 |
| Antitumor | Bonaccorsi et al., 2008; Soica et al., 2014 | |
| Swertanone | Antiinflammatory | Kumar et al., 2003; Tabassum et al., 2012 |
| Syringaresinol | Hepatoprotective | Chakravarty et al., 1994 |
| Bellidifolin | Hypoglycemic | Basnet et al., 1995 |
| Isobellidifolin | Hypoglycemic | Basnet et al., 1995 |
| 1-Hydroxy-3,5,8-trimethoxyxanthone | Antimalarial | Mandal and Chatterjee, 1994 |
| 1-Hydroxy-3,7,8-trimethoxyxanthone | Spasmogenic agent | Ateufack et al., 2007 |
| Antiulcerogenic | Ateufack et al., 2014 | |
| 1,5,8-trihydroxy-3-methoxyxanthone | Blood sugar lowering | Ghosal et al., 1973 |
| β-Amyrin | Anti-inflammatory | Holanda et al., 2008 |
| Antimicrobial, antifungal | Vázquez et al., 2012 | |
| Chiratol | Anti-inflammatory | Banerjee et al., 2000 |