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. 2016 Jan 12;9:517. doi: 10.3389/fncel.2015.00517

Figure 6.

Figure 6

AR-mediated bcl-2, bcl-xl, and bax expressions depended on the activation of p90RSK and CREB. OGD/R were applied, and then incubation with AR (3, 10, 30 μM) or indicated inhibitors for indicated times. (A) Representative result of CREB phosphorylation alterations in neurons experiencing 6 h AR treatment or inhibitor(s) blocking after OGD/R, and this quantification data were described in (B). (C) Representative results of bcl-2, bcl-xl, and bax expressions changes in neurons experiencing 8 h AR treatment or inhibitor(s) blocking after OGD/R, and quantification data from four individual experiments were described in (D) bcl-2, (E) bcl-xl, and (F) bax. Bcl-2 (G), bcl-xl (H), and bax (I) gene expressions changes in neurons experiencing 8 h AR treatment or inhibitor(s) blocking after OGD/R were evaluated using qRT-PCR assay, and quantification data were from four individual experiments. Results mentioned-above were mean ± SD for four individual experiments which, for each condition, were performed in quadruplicate. *P < 0.05; **P < 0.01; ***P < 0.001.