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. 2016 Jan 12;9:517. doi: 10.3389/fncel.2015.00517

Figure 7.

Figure 7

The effect of AR on the phosphorylation of ERK1/2, cPKC, p90RSK, CREB and bcl-2, bcl-xl and bax expressions in cortex of MCAO rats. The vehicle group and AR groups underwent MCAO while the sham group underwent the same surgical procedure without the filament inserted. After MCAO performed, rats in AR groups were intraperitoneally administrated with AR (8, 16, and 32 mg/kg) for 3 days. (A) Representative results of ERK1/2, cPKC, p90RSK, CREB phosphorylation alterations and bcl-2, bcl-xl, and bax expressions changes in MCAO rats, and quantification data were described in (B) ERK1/2 phosphorylation level, (C) PKCα phosphorylation level, (D) PKCβ1/β2 phosphorylation level, (E) PKCγ phosphorylation level, (F) p90RSK phosphorylation level, (G) CREB phosphorylation level, and (H) bcl-2, (I) bcl-xl, and (J) bax expressions. Results mentioned-above were described as mean ± SD (n = 8). *P < 0.05; **P < 0.01; ***P < 0.001.