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(a) Three-dimensional MR angiogenesis maps of control and integrin-targeted fumagillin NP in Vx2 model. (b) Angiogenesis contrast before and 1 week after a fumagillin or control NPs in hyperlipidemic rabbits. (c) Decreased arthritic score and ankle thickness following targeted fumagillin in the K/BxN model of inflammatory arthritis. (Reprinted with permission from Refs 29–31. Copyright 2008, 2006, and 2009)
