Table 4. Validation of NA inhibition ability for small molecules.
Concentration (μg/ml) | Mean CPE ± S.D. | ER(%) | Mean fluorescence intensity (A.U ± S.D.) | |
---|---|---|---|---|
Chlorogenic acid | 50 | 2.00 ± 0.00*** | 52.7*** | 2.25 ± 0.39*** |
25 | 2.25 ± 0.50*** | 43.8*** | 3.31 ± 0.25*** | |
12.5 | 3.00 ± 0.50** | 25.6** | 4.11 ± 0.32*** | |
6.25 | 3.33 ± 0.50* | 17.8* | 4.43 ± 0.38*** | |
3.125 | 3.67 ± 0.58 | 10.2 | 4.75 ± 0.45** | |
1.563 | 4.00 ± 0.00 | 5.3 | 5.67 ± 0.57 | |
Quercetin | 50 | 1.67 ± 0.00*** | 59.3*** | 1.74 ± 0.16*** |
25 | 2.00 ± 0.00*** | 50.6*** | 2.67 ± 0.20*** | |
12.5 | 2.33 ± 0.58*** | 41.5** | 3.50 ± 0.26*** | |
6.25 | 3.00 ± 0.00** | 26.3** | 4.34 ± 0.31*** | |
3.125 | 3.33 ± 0.58* | 19.4* | 4.63 ± 0.41*** | |
1.563 | 3.33 ± 0.58* | 17.7* | 5.48 ± 0.52* | |
Zanamvir | 50 | 0.00 ± 0.00*** | 87.3*** | 1.24 ± 0.11*** |
25 | 0.00 ± 0.00*** | 84.1*** | 1.73 ± 0.15*** | |
12.5 | 0.67 ± 0.58*** | 79.6*** | 2.20 ± 0.25*** | |
6.25 | 1.25 ± 0.50*** | 68.8*** | 3.27 ± 0.29*** | |
3.125 | 2.67 ± 0.58*** | 35.3** | 3.34 ± 0.40*** | |
1.563 | 2.75 ± 0.50** | 31.7** | 5.35 ± 0.48** | |
Placebo | – | 4.00 ± 0.00 | – | 7.54 ± 0.61 |
Normal | – | 0.00 ± 0.00 | – | 1.71 ± 0.14 |
*p < 0.05, **p < 0.01, ***p < 0.001, the values were compared with placebo controls.