Figure 4.

Effects of acute pretraining (a) or posttraining (b) CB2 receptor antagonist AM 630 or saline administration on the latency index (LI) in the PA test in mice. AM 630 (0.25, 0.5, 1.0, 2.0, and 3.0 mg/kg; ip) or vehicle was administered 30 min before the first trial (a) or immediately after the first trial (b) and the mice were retested 24 h later; n = 8–12; the means ± SEM; ^∗ p < 0.05; ^∗∗ p < 0.01 versus vehicle-treated control group; Tukey's test.