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. 2015 Dec 29;2016:7383724. doi: 10.1155/2016/7383724

Figure 5.

Figure 5

Catalytic activities of ERK1/2 (represented as ERK1/2-mediated phosphorylation of Elk1) in cytosolic and nuclear fractions of FC (a) and hippocampus (c) obtained from TC (tested controls), non-learned helpless (non-LH), and learned helpless (LH) rats. β-actin was used as normalizer. Mean ± SD of Elk1 phosphorylation in cytosolic and nuclear fractions of FC (b) and hippocampus (d) of TC, non-LH, and LH rats (n = 6/group). Overall group differences among TC, non-LH, and LH rats are as follows. FC: cytosolic, df = 2,15, F = 33.71, and P < 0.001; nuclear, df = 2,15, F = 25.93, and P < 0.001. Hippocampus: cytosolic, df = 2,15, F = 16.63, and P < 0.001; nuclear, df = 2,15, F = 25.57, and P < 0.001.