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. 2015 Dec 29;2016:7383724. doi: 10.1155/2016/7383724

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Copyright © 2016 Y. Dwivedi and H. Zhang.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Immunolabeling of p-ERK1/2 in FC (a) and hippocampus (c) obtained from tested control (TC), non-learned helpless (non-LH), and learned helpless (LH) rats. β-actin was used as endogenous control. Mean ± SD of ERK1 and ERK2 phosphorylation in FC and hippocampus of TC, non-LH, and LH rats (n = 6/group) is depicted in (b) and (d), respectively. Overall group differences in the 3 groups are as follows. FC: ERK1, df = 2,15, F = 19.93, and P < 0.001; ERK2, df = 2,15, F = 28.04, and P < 0.001. Hippocampus: ERK1, df = 2,15, F = 26.12, and P < 0.001; ERK2, df = 2,15, F = 48.89, and P < 0.001.