Table 7.
Results of meta-analyses in our study.
| Number of studies | Assessment | Number of studies | Model, pooled relative risk estimates (95% CI) | Heterogeneity | Publication bias | ||||
|---|---|---|---|---|---|---|---|---|---|
| χ 2 | I 2% | p | Begg's p | Egger's p | |||||
| Cell-based versus cell-free | 7 | Excellent and good results | 5 | Fixed, OR, 4.27 (2.19–8.34) |
5.17 | 22.7 | 0.27 | 0.221 | 0.269 |
| Mean score and standard deviation | 6 | Random, WMD, 10.11 (2.69–16.53) |
22.93 | 78.2 | 0 | 1 | 0.953 | ||
|
| |||||||||
| Traditional ACI versus MACT | 6 | Excellent and good results | 5 | Fixed, OR, 0.49 (0.30–0.82) |
1.50 | 0 | 0.83 | 0.086 | 0.088 |
| Graft hypertrophy | 4 | Fixed, OR, 2.43 (1.00–5.94) |
3.94 | 23.8 | 0.27 | 0.734 | 0.241 | ||
| Frequency of reoperation | 3 | Fixed, OR, 1.34 (0.53–3.37) |
2.78 | 28.1 | 0.25 | 1 | 0.593 | ||
OR: odd ratio; CI: confidence interval; WMD: weighted mean difference; ACI: autologous chondrocyte implantation; MACT: matrix-assisted autologous chondrocyte transplantation.