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Primary antagonism data for the hybrid compound library in the E. coli LasR reporter strain. Compounds were evaluated at 50 μM in the presence of an EC70 of OdDHL (5 nM). Culture treated with only 5 nM OdDHL was set to 0% antagonism/100% activity. Culture treated with only DMSO was set to 100% antagonism/0% activity (see the Supporting Information for full assay details).
