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. 2016 Jan 12;9:71. doi: 10.3389/fnint.2015.00071

Figure 2.

Figure 2

PB+PER exposed mice demonstrated disinhibition, 13 months post exposure, as revealed by Elevated Plus Maze testing. EPM testing revealed that PB+PER mice spent significantly less time in the closed arms (A), and a significantly larger proportion of time in the open arms (B) as compared to their controls. No differences were noted between the two groups when examining (C) number of visits to the Closed Arms (#). PB+PER mice visited the open arms (#) more times as compared to the control mice (D). In addition, exposed mice spent more time in the center as compared to the control mice (E). Therefore, the exposed mice exhibited reduced anxiety-like behaviors. No differences were noted between the two groups when examining the number of visits to the center area (the junction between the closed and the open arms) (F). Furthermore, EPM testing revealed that there were no differences between exposed and control mice when examining (G) Cumulative distance moved (cm) and (H) Velocity (cm/s). *p < 0.05; **p < 0.01; ***p < 0.005.