Table 2.
Top SNPs from GEMMA mixed model analysis of Sequenom genotyping data in the discovery cohort
| Chr | bp | P-value likelihood ratio test | Annotation |
|---|---|---|---|
| 14 | 34391965 | 4.00E-04 | Intron ARHGAP26 |
| 14 | 35363931 | 1.24E-03 | Intron FCHSD1 |
| 14 | 16854653 | 2.23E-03 | Synonymous exon 5 CCNG1 |
| 14 | 34803961 | 2.25E-03 | Downstream SPRY4 |
| 14 | 37127327 | 2.25E-03 | Downstream UBE2D2 |
| 10 | 57350466 | 2.28E-03 | Intron PDSS2 |
| 14 | 18034557 | 5.97E-03 | Intron GABRA1 |
| 10 | 55605051 | 6.27E-03 | Downstream PREP |
| 14 | 18059791 | 6.96E-03 | Intron GABRA1 |
| 21 | 50348105 | 7.37E-03 | Intron SEMA5A |
| 14 | 16782922 | 9.55E-03 | Synonymous exon 1 MAT2B |
| 21 | 53443537 | 9.69E-03 | Downstream ADAMTS1 |
| 14 | 18029925 | 1.13E-02 | Synonymous exon 8 GABRA1 |
| 2 | 99999249 | 1.24E-02 | Intergenic |
| 21 | 48664783 | 2.20E-02 | Intron CTNND2 |
| 14 | 18528304 | 2.22E-02 | Intron GABRB2 |
| 10 | 57303131 | 2.23E-02 | Intron PDSS2 |
| 21 | 50383063 | 2.58E-02 | Intron SEMA5A |
| 16 | 14358731 | 2.69E-02 | Nonsynonymous exon 8 CNTN6 |
| 10 | 56817838 | 2.92E-02 | Intron QRSL1 |
| 21 | 49882816 | 3.39E-02 | Synonymous exon 1 TAS2R1 |
| 1 | 118771557 | 3.64E-02 | Intron PPCDC |
| 1 | 118401125 | 4.42E-02 | Downstream SNUPN |
Chr chromosome, bp base pair