Fig. 2.

Flow cytometry immunophenotyping of DPN-treated T lymphocytes. Flow cytometry analysis of T cell activation markers was carried out in CD4⁺ and CD8⁺ T lymphocytes from randomly selected SLE patients with SLEDAI-2K <6 and ≥6 (n = 5 for group), arbitrarily chosen as representative of the whole series, and treated with DPN (10 nM) for 48 h. Data are represented as box plots displaying medians, 25th and 75th percentiles as boxes, and the lowest and highest values as whiskers. *p < 0.05 versus untreated cells