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. 2016 Jan 12;14:3. doi: 10.1186/s12951-015-0154-9

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© Angelov et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Impedance dynamics of electrodes coated with different nanoparticle sizes (<10 nm; 50 nm; mixture of both) and the uncoated group (NoNP) measured in vitro, 10 days postoperatively and after each of the three stimulation weeks (in vivo). Data are given as means + SEM. Significant difference between groups is indicated with (asterisks), while the circle (o) shows a significant effect between different test times (ANOVA with post hoc Tukey’s test p < 0.05). Inserted graph shows comparison of absolute impedance increase before operation and after the 3rd week of stimulation. Significant difference is indicated with asterisk (*; t test p < 0.05)