Table 4.
Putatively functional variants with an Fst score > = 0.75 in genes in the ‘adrenaline and noradrenaline biosynthesis’ pathway
| Gene ID | Gene name | Position [chr:position] | Nucleotide change [Dog/Wolf] | Predicted effect |
|---|---|---|---|---|
| DDC | Dopa decarboxylase [Aromatic-L-Amino-Acid decarboxylase] | 18:1806717 | C/T | Missense [R/Q] |
| MAOA | Amine oxidase [flavin-containing] A | X:37747023 | T/C | 3‘-UTR |
| MAOB | Amine oxidase [flavin-containing] B | X:37766049 | C/T | 3‘-UTR |
| SLC6A3 | Sodium-dependent dopamine transporter member 3 | 34:11239621 | C/T | Splice region, intronic |
| SLC6A17 | Sodium-dependent neutral amino acid transporter member 17 | 6:41776709 | C/A | 3‘-UTR |
| SLC6A19 | Sodium-dependent neutral amino acid transporter member 19 | 34:11329939 | G/A | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30614788 | C/T | Missense [S/N] |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30607948 | G/A | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30607975 | T/C | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608088 | T/C | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608209 | G/A | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608212 | T/C | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608354 | A/G | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608375 | C/T | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608864 | A/G | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:30608989 | C/T | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:37750228 | T/A | 3‘-UTR |
| SNAP29 | Synaptosomal-associated protein 29 | 26:38554416 | G/A | 3‘-UTR |
| STX7 | Syntaxin-7 | 1:25559797 | T/C | 3‘-UTR |
| TH | Tyrosine 3-monooxygenase | 18:46331581 | G/A | Splice region, intronic |