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. 2016 Jan 12;7:5. doi: 10.1186/s13293-015-0056-4

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© Johansson et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Comparison of the observed spatial signal distribution to randomized signal distributions in male MO for NLGN4X/Y. The frequency of pixels of varying intensity ratios of X and Y for NLGN4X/Y in male SC (E32_S84) are displayed in the histogram in a. A cutoff of 80 % colour purity was set to classify pixels as X dominant and Y dominant, displayed in the histogram as a blue field and a pink field, respectively. Pixels deviating more than 3 SD are shown as yellow dots on the blue line and then plotted in b visualize the location of the pixels over-represented in the sample tissue compared to the randomized data set. The proportions of X-dominant, Y-dominant and mixed pixels in the analysed samples are shown for all samples next to their respective randomized data set in c for NLGN4X/Y and in d for PCDH11X/Y. Relative pixel frequency from the random distributions for all samples is shown in c and d.