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Overlap of GPP and 13. a) Allylic site of 13-TcFPPS complex. 13, amino acids are shown in stick representation (pink). Portion of the 2mFo-DFc electron density corresponding to the inhibitor 13 is shown in grey color. b) Structural overlap of 13-TcFPPS complex with the chicken FPPS-GPP complex (PDB: 1UBW). TcFPPS is shown in ribbon model (green). The ligands 13 (pink) and GPP (blue) in stick representation. Only GPP of the chicken FPPS is shown in the figure.
