Figure 6.
Positive correlation between reduced neuronal damage and ER stress in the DHA-treated brains. (a) Microscopic fluorescent images of sham, TBI, and TBI + DHA brains stained with FJ-C. Arrow: site of surgery. (b) Representative confocal images show FJ-C stained neurons in the IL frontal cortex peri-lesion at 3 to 21 days post-TBI. Inset: CL frontal cortex. Arrowhead: FJ-C positive degenerating neurons. Inset shows CL frontal cortex tissue at the same location. (c) Summary data of FJ-C positive cells per mm2. Values are mean ± SE (n = 4). (d) Correlation analysis of CHOP+ cells versus FJ-C+ cells (R = .588, p < .05, n = 14). *p < .05, one-way ANOVA test used.