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. 2015 Oct 19;7(5):1759091415609613. doi: 10.1177/1759091415609613

Table 1.

Patient Summary.

Patient numbera Diagnosis Age Gender MRI activity AGS scoreb % AGS+ B cellsc
1 RRMS 19 F GD+ 17.6 22
2 ONCIS 40 F GD+ 6.1 50
3 ONCIS 40 F GD+ 10.7 27
4 TMCIS 28 F GD+ 17.9 18
5 TMCIS 20 F GD+ 16.7 28
6 TMCIS 33 M GD+ 22.3 13
7 RRMS 32 F GD+ 14.0 14
8 RRMS 44 F GD+ 14.0 11
9 RRMS 35 F GD+ 15.0 23
10 ONCIS 34 F GD+ 13.1 25
11 TMNMO 57 F GD+ 13.8 12

Note. AGS = antibody gene signature; GD+ = gadolinium enhancing lesion positive; F = female; M = male; MRI = magnetic resonance imaging; ONCIS = clinically isolated syndrome with optic neuritis symptoms; RRMS = relapsing remitting multiple sclerosis; TMCIS = transverse myelitis; TNMO = transverse myelitis that converted to neuromyelitis optica.

a

Overall antibody repertoire data were originally presented for Patient 7 in (Monson et al., 2005), Patients 8 and 9 in (Harp et al., 2007), Patients 4, 5, and 6 in the study by Ligocki et al. (2013) and Patients 1, 3, and 10 in the study by Rounds et al. (2014). bAGS scores were originally presented for Patients 7 to 9 in the study by Cameron et al. (2009) and Patients 1, 3 to 6, and 10 in the study by Rounds et al. (2014). cAGS+ B cells indicate percent of B cells in the CSF of the patient that had 2 or more mutated AGS codons.