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. Author manuscript; available in PMC: 2016 Mar 5.
Published in final edited form as: J Phys Chem B. 2015 Feb 20;119(9):3743–3754. doi: 10.1021/acs.jpcb.5b00212

Figure 4.

Figure 4

Energy landscape surfaces for conformational changes (ATSB) in RNase A. pH-dependent changes in enthalpy (left) and entropy (right) are depicted for Cluster 1 (top), 2 (middle), and R33 (bottom). Data were obtained from temperature dependent NMR relaxation experiments. In all cases conformation A is set at a reference value of 0 kcal/mol.