Fig. 3.

ROS metrics are increased with PCB126 treatment with no difference observed between WT and MTKO mice.

Hepatic ROS was increased with PCB126 as was the fragmented DNA in whole blood lymphocytes as measured by the COMET assay in both WT and MTKO animals. ROS responsive genes were induced with PCB126 exposure but no difference observed between genotypes. (Bars are standard error; * represents p < 0.05; two-way ANOVA; n = 6)