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MTKO mice are susceptible to renal micronutrient disruption caused by PCB126.
Renal copper, zinc, and manganese are all decreased in the MTKO animals following PCB126 administration. Renal Se is unaffected by both loss of metallothionein and PCB126 treatment. (Bars are standard error; * represents p < 0.05; two-way ANOVA; n = 6).
