Table 3.
Pretreatment PL in tissue by ML phenotype and severity
| ML phenotype and severity | Number | PL | |||
|---|---|---|---|---|---|
| Mean | SD | Median* | Range | ||
| Phenotype | |||||
| Primary ML | 5 | 262,547.7 | 524,968.2 | 94.7 | 1.33–1,050,000 |
| Classic ML | 39 | 126,381.2 | 414,086.5 | 218.0 | 1.08–2,274,247.5 |
| Severity | |||||
| Mild | 23 | 78,976.2 | 240,004.2 | 51.508 | 1.08–948,000 |
| Moderate | 7 | 5,759.5 | 14,487.8 | 95.4 | 2.4–38,600 |
| Severe | 14 | 329,041.9 | 688,788.7 | 1,285.0 | 80.7–2,274,247.5 |
CL = cutaneous leishmaniasis; ML = mucosal leishmaniasis; PL = parasite load; SD = standard deviation.
Primary ML, which occurred in the absence of history of prior CL; classic ML, which occurred after a documented history of CL; mild, isolated nasal involvement; moderate, nasal and oral involvement; severe, nasal and laryngeal involvement with or without oral involvement.
*
P = 0.005 by one-way analysis of variance on ranks (with Dunn's post hoc test) for severity of ML.