Table 3.

Association between demographic and clinical variables and ELISA OD values^* (longitudinal analysis)

Variable	Univariable analysis			Multivariable analysis
	Coefficient†	95% CI	P	Coefficient†	95% CI	P
Age (years)	−0.0014	−0.0046 to 0.0017	0.375	0.0003	−0.0026 to 0.0032	0.842
Male gender	0.0828	−0.0357 to 0.2012	0.171	0.0608	−0.0458 to 0.1674	0.264
Cyst diameter (mm)‡	0.0033	0.002–0.0046	< 0.001	0.0025	0.0012–0.0038	< 0.001
Number of cysts	0.0919	0.0241–0.1597	0.008	0.0784	0.0141–0.1427	0.017
Type of cyst‡
Active vs. inactive	0.1313	0.0623–0.2004	< 0.001	0.0982	0.029–0.1675	0.005
Transitional vs. inactive	0.2302	0.1467–0.3137	< 0.001	0.1879	0.1036–0.2722	< 0.001
Time between treatment and serum collection
≤ 12 months	0.075	0.0113–0.1388	0.021	0.0857	0.0247–0.1468	0.006
> 12 months	−0.0144	−0.0773–0.0484	0.652	0.0113	−0.0484 to 0.0709	0.711

CI = confidence interval; ELISA = enzyme-linked immunosorbent assay; OD = optical density.

^*Log transformed.

^†The coefficient indicates the mean change of log-transformed ELISA OD per unit change of the independent variable.

^‡Data refer to the most active, and, when more cysts of the same stage were present, according to the cyst of largest diameter.