. 2016 Jan 12;11(1):e0147065. doi: 10.1371/journal.pone.0147065

Table 5. Addition of smoking to CHA₂DS₂-VASc in prediction of 5-year risk of ischemic stroke or cardiovascular death, Atherosclerosis Risk in Communities (ARIC) study from 1987 to 2006.

	C-statistic (95% CI)	Category-based NRI (95% CI)	Relative IDI (95% CI)
CHA₂DS₂ -VASc	0.701 (0.665–0.737)	N/A	N/A
CHA₂DS₂ -VASc + Smoking	0.712 (0.677–0.746)	0.040 (-0.017 to 0.096)	0.043 (-0.012 to 0.104)

IDI, integrated discrimination improvement; NA, not applicable; NRI, net risk improvement

Table 5. Addition of smoking to CHA2DS2-VASc in prediction of 5-year risk of ischemic stroke or cardiovascular death, Atherosclerosis Risk in Communities (ARIC) study from 1987 to 2006.