Fig 3. PD-1 expression by MTB-specific T-cells secreting IFN-γ is increased in active TB /HIV co-infection.

Graphs show percentage, median and IQR of PD-1 expression on CD4+ subsets secreting IFN-γ-only (top left), IFN- γ and TNF-α (top right) and IFN-γ, IL-2 and TNF-α (bottom left) following overnight stimulation with PPD. Individuals without a positive response were excluded. p values show Kruskal-Wallis test with Dunn’s post-test comparison.