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. Author manuscript; available in PMC: 2016 Jan 12.
Published in final edited form as: Clin Cancer Res. 2014 Oct 16;20(24):6559–6569. doi: 10.1158/1078-0432.CCR-14-1784

Figure 1. Members of the DLK1-DIO3 miRNA cluster (miR-154/154* and miR-379) are overexpressed in aggressive bone metastatic EMT models of human PCa.

Figure 1

(A) miRNA expression of miR-154/154* and miR-379 in PCa models (mesenchymal cells ARCaPM compared to ARCaPE and LNCaP verses C4-2 PCa cells) by qRT-PCR analysis. (B) miRNA stained or miR-154* stained PCa mouse bone metastatic models (C4-2 and ARCaPM cells) assayed by ISH-QD analysis (Magnification 40X). miR-154* stained in red, nucleus stained with DAPI. (C), (D) miRNA expression of miR-154/154* and miR-379 in H9 embryonic stem cells and iPS cells by qRT- PCR. (E) miRNA expression in EMT models in PCa, mesenchymal cells-ARCaPM, epithelial cells-ARCaPE and ARCaPM KDHFE1, assayed by qRT-PCR. *: p<0.05 was considered to be statistically significant by one way ANOVA-Tukey analysis.