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. Author manuscript; available in PMC: 2016 Oct 28.
Published in final edited form as: Small. 2015 Aug 21;11(40):5360–5368. doi: 10.1002/smll.201501573

Figure 1.

Figure 1

Characterization of as-synthesized polycaprolactone-based micelle-SNAs. (a) 1% agarose gel electrophoresis; nucleic acids were stained with ethidium bromide; (b) A typical DLS measurement of micelle-SNAs derived from (top) linear and (bottom) brush block copolymer structures; (c) Melting transition behaviour for micelle-SNAs hybridized to complementary 15 nm AuNP-SNAs; (black trace) micelle-SNAs made from linear structures and (red trace) micelles made from the brush architecture; (d) Cryogenic TEM images of micelle-SNAs derived from brush block copolymer. Both DBBC-SNA and LDBC-SNA nanoparticles remain intact under cryogenic conditions and are relatively uniform in size with diameters ~ 30-50 nm.