Figure 3.
Effects of ATM and CHK2 knockdowns on p53 and apoptotic responses in Asc-restored H460. (A) ATM-related phosphorylation in cells collected immediately after 3-hr Cr(VI) exposure. (B) Activation of p53 in cells immediately after Cr(VI) exposure. (C,D) Western blots of cells collected at 24 hr post–Cr exposure. SCR, scrambled.