Table 1.
Administered doses and available biological samples.
| Compounds | Administered dosea | Samplesb | |||
|---|---|---|---|---|---|
| Reference | mg/kg/day | Rats (n) | Urine | Serum | |
| Experiment 1 | |||||
| Diethyl phthalate | NOAEL/10 | 173.5 | 5 | Yes | No |
| NOAEL/100 | 17.35 | 5 | Yes | No | |
| NOAEL/200 | 8.68 | 5 | Yes | No | |
| Methyl paraben | NOAEL/10 | 105 | 5 | Yes | No |
| NOAEL/100 | 10.5 | 5 | Yes | No | |
| NOAEL/200 | 5.25 | 5 | Yes | No | |
| Triclosan | NOAEL/10 | 5 | 5 | Yes | No |
| NOAEL/100 | 0.5 | 5 | Yes | No | |
| NOAEL/200 | 0.25 | 5 | Yes | No | |
| Control | Olive oil | — | 5 | Yes | No |
| Experiment 2 | |||||
| Diethyl phthalate | NOAEL/200 | 8.675 | 5 | Yes | Yes |
| NOAEL/10,000 | 0.1735 | 5 | Yes | Yes | |
| NOAEL/100,000 | 0.01735 | 5 | Yes | Yes | |
| Methyl paraben | NOAEL/200 | 5.25 | 5 | Yes | Yes |
| NOAEL/10,000 | 0.105 | 5 | Yes | Yes | |
| NOAEL/100,000 | 0.0105 | 5 | Yes | Yes | |
| Triclosan | NOAEL/200 | 0.25 | 5 | Yes | Yes |
| NOAEL/1,000 | 0.05 | 5 | Yes | Yes | |
| NOAEL/10,000 | 0.005 | 5 | Yes | Yes | |
| Control | Olive oil | — | 5 | Yes | Yes |
| NOAEL, no observed adverse effect level. aNOAEL (mg/kg/day) for diethyl phthalate = 1,735; methyl paraben = 1,050; triclosan = 50. bOnly pooled urine samples available in experiment 1; individual urine and serum samples available in experiment 2. | |||||